706-722-9011

Locations

Piedmont Augusta

1350 Walton Way
Augusta, GA 30901

Piedmont Augusta Breast Health Center

818 St. Sebastian Way, Suite 205
Augusta, GA 30901

Piedmont Augusta Summerville Campus

2260 Wrightsboro Road
Augusta, GA 30904
Piedmont Augusta
ER
Wait
Time
32
min *

Serving Our Community for Over 200 Years

Piedmont Augusta (formerly University Hospital) serves the Augusta-Richmond County area and 25 counties across two states. The hospital is an 812-bed acute-care facility and part of a multi-campus system that includes three hospitals, a heart and vascular center, prompt and primary care, home health and private physician offices. Founded in 1818 as City Hospital, Piedmont Augusta has since moved through four facilities to its present location, which opened in 1970, and includes its Summerville Campus on Wrightsboro Road.

Piedmont Augusta offers state-of-the-art, comprehensive medical and surgical care that includes emergency services, cardiovascular, orthopaedics, neuroscience, oncology, bariatrics and weight management, robotic surgery and women’s services. Our cardiovascular services include state-of-the-art treatments for advanced cardiac conditions – including the Left Ventricular Assist Device, Transcatheter Aortic Valve Replacement and MitraClip for severe mitral valve regurgitation – and vascular conditions – such as the Fenestrated Abdominal Aortic Aneurysm Graft and the Penumbra Indigo® System for minimally invasive clot removal in arteries and veins.

Piedmont Augusta at Summerville Campus, formerly University Hospital, was founded in 1952 and joined the Piedmont family on March 1, 2022. The hospital is known for its comprehensive diagnostic services, including cardiac catheterization, magnetic resonance imaging, and osteoporosis treatment.

It offers a 24-hour, 15-bed Emergency Department, a 12-bed inpatient unit and new and enhanced imaging services. Outpatient services include Wound & Hyperbaric Services, Diabetes Services, Full-service Lab, Sleep Lab, Coumadin Clinic, Primary Care and Piedmont Heart. It offers these services in the Summerville Medical Building and in the newly renovated Occupational Medicine suite.


Other awards and recognition include:

  • Comprehensive Stroke Center
  • The American Heart Association’s Gold Plus Get With the Guidelines ®- Stroke Quality Award
  • The American Heart Association’s Target: Stroke(sm) Honor Roll Therapy award
  • The American Heart Association’s Target: Type 2 Honor Roll award
  • ACE™ Accreditation by Accreditation for Cardiovascular Excellence
  • IAC® Accreditation by Intersocietal Accreditation Commission
  • Credentialed DNV GL - Healthcare VAD Facility/CMS Certified Ventricular Assist Device Program
  • Piedmont Augusta receives Cycle Five Accreditation from Society of Cardiovascular Patient Care
  • BCBS Association designates Piedmont Augusta a Blue Distinction Center+ for Cardiac Care
  • Level 1 Emergency Cardiac Care Center designation from the Georgia Department of Public Health
  • Accreditation by the Commission on Cancer, a program of the American College of Surgeons
  • Credentialed as a Ventricular Assist Device facility by DNV GL
  • Full Cycle Five Chest Pain Center with Primary PCI accreditation from the Society of Cardiovascular Patient Care
  • Blue Distinction Center+ designation for knee and hip replacement from Blue Cross Blue Shield®
  • Blue Distinction Center+ designation for spine surgery from Blue Cross Blue Shield®
  • Accreditation by the National Accreditation Program for Breast Centers for Piedmont Augusta’s Breast Health Center, the first established breast center in our area
  • Named No. 1 in the region by “US News & World Report” and ninth in Georgia
  • Ranked “High Performing” in nine reportable conditions or procedures by “US News & World Report,” including:
    • Chronic obstructive pulmonary disease
    • Colon cancer surgery
    • Heart failure
    • Heart attack
    • Stroke
    • Kidney failure
    • Knee replacement
    • Hip replacement
    • Diabetes

Piedmont Augusta (formerly known as University Hospital) became part of Piedmont Healthcare on March 1, 2022 – expanding quality health services to our community.

*Piedmont Augusta complies with applicable Federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

Piedmont MyChart

Download Piedmont MyChart

  • Connect with your care team
  • See your test results
  • Request Rx refills
  • eCheck-in before you walk in 

Download the app today!

Get Piedmont MyChart on Google Play Get Piedmont Mychart on iTunes App Store
Piedmont Augusta Hospital | Piedmont Healthcare
706-722-9011

Locations

Piedmont Augusta

1350 Walton Way
Augusta, GA 30901

Piedmont Augusta Breast Health Center

818 St. Sebastian Way, Suite 205
Augusta, GA 30901

Piedmont Augusta Summerville Campus

2260 Wrightsboro Road
Augusta, GA 30904
Piedmont Augusta
ER
Wait
Time
32
min *

Serving Our Community for Over 200 Years

Piedmont Augusta (formerly University Hospital) serves the Augusta-Richmond County area and 25 counties across two states. The hospital is an 812-bed acute-care facility and part of a multi-campus system that includes three hospitals, a heart and vascular center, prompt and primary care, home health and private physician offices. Founded in 1818 as City Hospital, Piedmont Augusta has since moved through four facilities to its present location, which opened in 1970, and includes its Summerville Campus on Wrightsboro Road.

Piedmont Augusta offers state-of-the-art, comprehensive medical and surgical care that includes emergency services, cardiovascular, orthopaedics, neuroscience, oncology, bariatrics and weight management, robotic surgery and women’s services. Our cardiovascular services include state-of-the-art treatments for advanced cardiac conditions – including the Left Ventricular Assist Device, Transcatheter Aortic Valve Replacement and MitraClip for severe mitral valve regurgitation – and vascular conditions – such as the Fenestrated Abdominal Aortic Aneurysm Graft and the Penumbra Indigo® System for minimally invasive clot removal in arteries and veins.

Piedmont Augusta at Summerville Campus, formerly University Hospital, was founded in 1952 and joined the Piedmont family on March 1, 2022. The hospital is known for its comprehensive diagnostic services, including cardiac catheterization, magnetic resonance imaging, and osteoporosis treatment.

It offers a 24-hour, 15-bed Emergency Department, a 12-bed inpatient unit and new and enhanced imaging services. Outpatient services include Wound & Hyperbaric Services, Diabetes Services, Full-service Lab, Sleep Lab, Coumadin Clinic, Primary Care and Piedmont Heart. It offers these services in the Summerville Medical Building and in the newly renovated Occupational Medicine suite.


Other awards and recognition include:

  • Comprehensive Stroke Center
  • The American Heart Association’s Gold Plus Get With the Guidelines ®- Stroke Quality Award
  • The American Heart Association’s Target: Stroke(sm) Honor Roll Therapy award
  • The American Heart Association’s Target: Type 2 Honor Roll award
  • ACE™ Accreditation by Accreditation for Cardiovascular Excellence
  • IAC® Accreditation by Intersocietal Accreditation Commission
  • Credentialed DNV GL - Healthcare VAD Facility/CMS Certified Ventricular Assist Device Program
  • Piedmont Augusta receives Cycle Five Accreditation from Society of Cardiovascular Patient Care
  • BCBS Association designates Piedmont Augusta a Blue Distinction Center+ for Cardiac Care
  • Level 1 Emergency Cardiac Care Center designation from the Georgia Department of Public Health
  • Accreditation by the Commission on Cancer, a program of the American College of Surgeons
  • Credentialed as a Ventricular Assist Device facility by DNV GL
  • Full Cycle Five Chest Pain Center with Primary PCI accreditation from the Society of Cardiovascular Patient Care
  • Blue Distinction Center+ designation for knee and hip replacement from Blue Cross Blue Shield®
  • Blue Distinction Center+ designation for spine surgery from Blue Cross Blue Shield®
  • Accreditation by the National Accreditation Program for Breast Centers for Piedmont Augusta’s Breast Health Center, the first established breast center in our area
  • Named No. 1 in the region by “US News & World Report” and ninth in Georgia
  • Ranked “High Performing” in nine reportable conditions or procedures by “US News & World Report,” including:
    • Chronic obstructive pulmonary disease
    • Colon cancer surgery
    • Heart failure
    • Heart attack
    • Stroke
    • Kidney failure
    • Knee replacement
    • Hip replacement
    • Diabetes

Piedmont Augusta (formerly known as University Hospital) became part of Piedmont Healthcare on March 1, 2022 – expanding quality health services to our community.

*Piedmont Augusta complies with applicable Federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

Piedmont MyChart

Download Piedmont MyChart

  • Connect with your care team
  • See your test results
  • Request Rx refills
  • eCheck-in before you walk in 

Download the app today!

Get Piedmont MyChart on Google Play Get Piedmont Mychart on iTunes App Store
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TOP

Orphenadrine (Injection route)

Pronunciation:

or-FEN-a-dreen

Brand Names:

  • Antiflex
  • Mio-Rel
  • Norflex
  • Orfro
  • Orphenate

Dosage Forms:

  • Solution

Classifications:

Therapeutic—

Skeletal Muscle Relaxant, Centrally Acting

Pharmacologic—

Antimuscarinic

Uses of This Medicine:

Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem .

Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects .

This medicine is available only with your doctor's prescription .

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies—

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Children—

Appropriate studies have not been performed on the relationship of age to the effects of orphenadrine in the pediatric population. Safety and efficacy have not been established .

Older adults—

No information is available on the relationship of age to the effects of orphenadrine in geriatric patients. However, elderly patients are more likely to have age-related heart, liver, or kidney problems which may require caution in patients receiving orphenadrine .

Breast-feeding—

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Potassium Chloride
  • Potassium Citrate

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alfentanil
  • Alprazolam
  • Amantadine
  • Amifampridine
  • Benzhydrocodone
  • Bromazepam
  • Buprenorphine
  • Butalbital
  • Butorphanol
  • Calcium Oxybate
  • Cannabidiol
  • Cannabis
  • Carbidopa
  • Carbinoxamine
  • Cetirizine
  • Clobazam
  • Clonazepam
  • Clozapine
  • Codeine
  • Cyclobenzaprine
  • Cyproheptadine
  • Daridorexant
  • Dexmedetomidine
  • Diazepam
  • Dihydrocodeine
  • Donepezil
  • Doxylamine
  • Esketamine
  • Fentanyl
  • Flibanserin
  • Foscarbidopa
  • Foslevodopa
  • Gabapentin
  • Gabapentin Enacarbil
  • Glucagon
  • Glycopyrrolate
  • Glycopyrronium Tosylate
  • Hydrocodone
  • Hydromorphone
  • Ketamine
  • Lacosamide
  • Lemborexant
  • LetibotulinumtoxinA-wlbg
  • Levocetirizine
  • Levodopa
  • Levorphanol
  • Lofexidine
  • Loxapine
  • Magnesium Oxybate
  • Meperidine
  • Methacholine
  • Methadone
  • Metoclopramide
  • Midazolam
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Olanzapine
  • Oliceridine
  • Oxycodone
  • Oxymorphone
  • Paliperidone
  • Pentazocine
  • Phenobarbital
  • Potassium Oxybate
  • Pregabalin
  • Primidone
  • Promethazine
  • Quetiapine
  • Remifentanil
  • Remimazolam
  • Revefenacin
  • Ropeginterferon Alfa-2b-njft
  • Scopolamine
  • Secretin Human
  • Sodium Oxybate
  • Sofpironium
  • Sufentanil
  • Tapentadol
  • Tiotropium
  • Topiramate
  • Tramadol
  • Trazodone
  • Zolpidem
  • Zuranolone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Perphenazine
  • Tizanidine

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Enlarged esophagus or
  • Enlarged prostate or
  • Glaucoma or
  • Intestinal blockage or
  • Myasthenia gravis or
  • Stomach ulcer or
  • Urinary tract blockage—Orphenadrine should not be used in patients with these conditions .
  • Heart problems (e.g., fast or irregular heartbeats, heart failure)—Use with caution. Orphenadrine may worsen these conditions .

Proper Use of This Medicine:

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins or into your muscle .

Precautions While Using This Medicine:

Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare
Cough
difficulty swallowing
dizziness
fast heartbeat
hives
itching
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
shortness of breath
skin rash
tightness in chest
unusual tiredness or weakness
wheezing
Incidence not known
Abdominal or stomach pain
diarrhea
fast, pounding, or irregular heartbeat or pulse
fever
glaucoma
joint or muscle pain
nausea
numbness or tingling of face, hands, or feet
redness and soreness of eyes
shortness of breath
sores in mouth
swelling of feet or lower legs
vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of Overdose
Blurred vision
confusion, delirium, or hallucinations
constipation
difficult urination
drowsiness
dry eyes, mouth, nose, or throat
eye pain
flushing or redness of face
troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
Anxiety
deep or fast breathing with dizziness
headache
irritability
itching skin
mental confusion
nervousness
numbness of feet, hands and around mouth
restlessness
trembling or shaking of hands or feet shakiness in legs, arms, hands, or feet
unusually large pupils of eyes
weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 3/11/2025

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

All rights reserved.



The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
All rights reserved.

Piedmont Augusta Hospital | Piedmont Healthcare
706-722-9011

Locations

Piedmont Augusta

1350 Walton Way
Augusta, GA 30901

Piedmont Augusta Breast Health Center

818 St. Sebastian Way, Suite 205
Augusta, GA 30901

Piedmont Augusta Summerville Campus

2260 Wrightsboro Road
Augusta, GA 30904
Piedmont Augusta
ER
Wait
Time
32
min *

Serving Our Community for Over 200 Years

Piedmont Augusta (formerly University Hospital) serves the Augusta-Richmond County area and 25 counties across two states. The hospital is an 812-bed acute-care facility and part of a multi-campus system that includes three hospitals, a heart and vascular center, prompt and primary care, home health and private physician offices. Founded in 1818 as City Hospital, Piedmont Augusta has since moved through four facilities to its present location, which opened in 1970, and includes its Summerville Campus on Wrightsboro Road.

Piedmont Augusta offers state-of-the-art, comprehensive medical and surgical care that includes emergency services, cardiovascular, orthopaedics, neuroscience, oncology, bariatrics and weight management, robotic surgery and women’s services. Our cardiovascular services include state-of-the-art treatments for advanced cardiac conditions – including the Left Ventricular Assist Device, Transcatheter Aortic Valve Replacement and MitraClip for severe mitral valve regurgitation – and vascular conditions – such as the Fenestrated Abdominal Aortic Aneurysm Graft and the Penumbra Indigo® System for minimally invasive clot removal in arteries and veins.

Piedmont Augusta at Summerville Campus, formerly University Hospital, was founded in 1952 and joined the Piedmont family on March 1, 2022. The hospital is known for its comprehensive diagnostic services, including cardiac catheterization, magnetic resonance imaging, and osteoporosis treatment.

It offers a 24-hour, 15-bed Emergency Department, a 12-bed inpatient unit and new and enhanced imaging services. Outpatient services include Wound & Hyperbaric Services, Diabetes Services, Full-service Lab, Sleep Lab, Coumadin Clinic, Primary Care and Piedmont Heart. It offers these services in the Summerville Medical Building and in the newly renovated Occupational Medicine suite.


Other awards and recognition include:

  • Comprehensive Stroke Center
  • The American Heart Association’s Gold Plus Get With the Guidelines ®- Stroke Quality Award
  • The American Heart Association’s Target: Stroke(sm) Honor Roll Therapy award
  • The American Heart Association’s Target: Type 2 Honor Roll award
  • ACE™ Accreditation by Accreditation for Cardiovascular Excellence
  • IAC® Accreditation by Intersocietal Accreditation Commission
  • Credentialed DNV GL - Healthcare VAD Facility/CMS Certified Ventricular Assist Device Program
  • Piedmont Augusta receives Cycle Five Accreditation from Society of Cardiovascular Patient Care
  • BCBS Association designates Piedmont Augusta a Blue Distinction Center+ for Cardiac Care
  • Level 1 Emergency Cardiac Care Center designation from the Georgia Department of Public Health
  • Accreditation by the Commission on Cancer, a program of the American College of Surgeons
  • Credentialed as a Ventricular Assist Device facility by DNV GL
  • Full Cycle Five Chest Pain Center with Primary PCI accreditation from the Society of Cardiovascular Patient Care
  • Blue Distinction Center+ designation for knee and hip replacement from Blue Cross Blue Shield®
  • Blue Distinction Center+ designation for spine surgery from Blue Cross Blue Shield®
  • Accreditation by the National Accreditation Program for Breast Centers for Piedmont Augusta’s Breast Health Center, the first established breast center in our area
  • Named No. 1 in the region by “US News & World Report” and ninth in Georgia
  • Ranked “High Performing” in nine reportable conditions or procedures by “US News & World Report,” including:
    • Chronic obstructive pulmonary disease
    • Colon cancer surgery
    • Heart failure
    • Heart attack
    • Stroke
    • Kidney failure
    • Knee replacement
    • Hip replacement
    • Diabetes

Piedmont Augusta (formerly known as University Hospital) became part of Piedmont Healthcare on March 1, 2022 – expanding quality health services to our community.

*Piedmont Augusta complies with applicable Federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

Piedmont MyChart

Download Piedmont MyChart

  • Connect with your care team
  • See your test results
  • Request Rx refills
  • eCheck-in before you walk in 

Download the app today!

Get Piedmont MyChart on Google Play Get Piedmont Mychart on iTunes App Store