Pulmonary ventilation/perfusion scan
A pulmonary ventilation/perfusion scan involves two nuclear scan tests to measure breathing (ventilation) and circulation (perfusion) in all areas of the lungs.
How the Test is Performed
A pulmonary ventilation/perfusion scan is actually 2 tests. They may be done separately or together.
During the perfusion scan, a health care provider injects radioactive albumin into your vein. You are placed on a movable table that is under the arm of a scanner. The machine scans your lungs as blood flows through them to find the location of the radioactive particles.
During the ventilation scan, you breathe in radioactive gas through a mask while you are sitting or lying on a table under the scanner arm.
How to Prepare for the Test
You do not need to stop eating (fast), be on a special diet, or take any medicines before the test.
A chest x-ray is usually done before or after a ventilation and perfusion scan.
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article
You wear a hospital gown or comfortable clothing that does not have metal fasteners.
How the Test will Feel
The table may feel hard or cold. You may feel a sharp prick when the IV is placed in the vein in your arm for the perfusion part of the scan.
The mask used during the ventilation scan may make you feel nervous about being in a small space (claustrophobia). You must lie still during the scan.
The radioisotope injection usually does not cause discomfort.
Why the Test is Performed
The ventilation scan is used to see how well air moves and blood flows through the lungs. The perfusion scan measures the blood supply through the lungs.
A ventilation and perfusion scan is most often done to detect a pulmonary embolus (blood clot in the lungs). It is also used to:
A pulmonary embolus is a blockage of an artery in the lungs. The most common cause of the blockage is a blood clot.Read Article Now Book Mark Article
- Detect abnormal circulation (shunts) in the blood vessels of the lungs (pulmonary vessels)
- Test regional (different lung areas) lung function in people with advanced pulmonary disease, such as COPD
Lung disease is any problem in the lungs that prevents the lungs from working properly. There are three main types of lung disease:Airway diseases -...Read Article Now Book Mark Article
The provider should take a ventilation and perfusion scan and then evaluate it with a chest x-ray. All parts of both lungs should take up the radioisotope evenly.
What Abnormal Results Mean
If the lungs take up lower than normal amounts of radioisotope during a ventilation or perfusion scan, it may be due to any of the following:
Risks are about the same as for x-rays (radiation) and needle pricks.
No radiation is released from the scanner. Instead, it detects radiation and converts it into an image.
There is a small exposure to radiation from the radioisotope. The radioisotopes used during scans are short-lived. All of the radiation leaves the body in a few days. However, as with any radiation exposure, caution is advised for pregnant or breastfeeding women.
There is a slight risk for infection or bleeding at the site where the needle is inserted. The risk with perfusion scan is the same as with inserting an intravenous needle for any other purpose.
Intravenous means "within a vein. " Most often it refers to giving medicines or fluids through a needle or tube inserted into a vein. This allows th...Read Article Now Book Mark Article
An allergy is an immune response or reaction to substances that are usually not harmful.Read Article Now Book Mark Article
A pulmonary ventilation and perfusion scan may be a lower-risk alternative to pulmonary angiography for evaluating disorders of the lung blood supply.
Pulmonary angiography is a test to see how blood flows through the lung. Angiography is an imaging test that uses x-rays and a special dye to see in...Read Article Now Book Mark Article
This test may not provide a definite diagnosis, particularly in people with lung disease. Other tests may be needed to confirm or rule out the findings of a pulmonary ventilation and perfusion scan.
This test has largely been replaced by CT pulmonary angiography for diagnosing pulmonary embolism. However, people with kidney problems or an allergy to contrast dye can more safely have this test.
Denis Hadjiliadis, MD, MHS, Paul F. Harron Jr. Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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Goldhaber SZ. Pulmonary embolism. In: Zipes DP, Libby P, Bonow RO, Mann, DL, Tomaselli GF, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019:chap 84.
Herring W. Nuclear medicine: understanding the principles and recognizing the basics. In: Herring W, ed. Learning Radiology: Recognizing the Basics. 4th ed. Philadelphia, PA: Elsevier; 2020:e24-e42.